When a dog and a police officer are injured together on the job. A life-saving surgery changes the course of history when Dog Man is born. Half dog, half man, Dog Man is sworn to protect and serve as long as he isn't distracted by squirrels, as he doggedly pursues his arch-nemesis: the feline supervillain Petey the Cat. But the rivalry between Dog Man and Petey is upended by the arrival of an adorable kitten clone of Petey, Lil Petey, who changes the game for both of them.